A Facile and High Yielding Synthesis of Symmetrical and Unsymmetrical Diarylalkynes Using Diethyl Dichloromethylphosphonate as Precursor
Résumé
The reaction, under internal quench conditions, of diethyl dichloromethylphosphonate and symmetrical or unsymmetrical diarylketones in the presence of n-BuLi, leads to the corresponding symmetrical or unsymmetrical diarylalkynes via a Fritsch-Buttenberg-Wiechell rearrangement in a simple, high yielding, onepot reaction.
Domaines
Chimie organiqueOrigine | Fichiers produits par l'(les) auteur(s) |
---|