A new simple method for the synthesis of 1-alkynylphosphonates using (EtO)2P(O)CCl3 as precursor
Résumé
1-Alkynylphosphonates 4 were obtained from (EtO) 2 P(O)CCl 3 1 and aldehydes in a one-pot procedure. It involves the formation of α-chlorovinyl phosphonate intermediates 3 by a Peterson olefination reaction followed by dehydrochlorination with LiHMDS.
Domaines
Chimie organiqueOrigine | Fichiers produits par l'(les) auteur(s) |
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