An inversion in the wiring of an intercellular signal: evolution of Wnt signaling in the nematode vulva. - Université Paris Cité Accéder directement au contenu
Article Dans Une Revue BioEssays Année : 2005

An inversion in the wiring of an intercellular signal: evolution of Wnt signaling in the nematode vulva.

Marie-Anne Félix

Résumé

Signal transduction pathways are largely conserved throughout the animal kingdom. The repertoire of pathways is limited and each pathway is used in different intercellular signaling events during the development of a given animal. For example, Wnt signaling is recruited, sometimes redundantly with other molecular pathways, in four cell specification events during Caenorhabditis elegans vulva development, including the activation of vulval differentiation. Strikingly, a recent study finds that Wnts act to repress vulval differentiation in the nematode Pristionchus pacificus, demonstrating evolutionary flexibility in the use of intercellular signaling pathways.
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Dates et versions

hal-00007750 , version 1 (02-08-2005)

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Marie-Anne Félix. An inversion in the wiring of an intercellular signal: evolution of Wnt signaling in the nematode vulva.. BioEssays, 2005, 27, pp.765-769. ⟨10.1002/bies.20275⟩. ⟨hal-00007750⟩
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