IDC2 and IDC3 , two genes involved in cell non-autonomous signaling of fruiting body development in the model fungus Podospora anserina - Université Paris Cité Access content directly
Journal Articles Developmental Biology Year : 2017

IDC2 and IDC3 , two genes involved in cell non-autonomous signaling of fruiting body development in the model fungus Podospora anserina

Abstract

Filamentous ascomycetes produce complex multicellular structures during sexual reproduction. Little is known about the genetic pathways enabling the construction of such structures. Here, with a combination of classical and reverse genetic methods, as well as genetic mosaic and graft analyses, we identify and provide evidence for key roles for two genes during the formation of perithecia, the sexual fruiting bodies, of the filamentous fungus Podospora anserina. Data indicate that the proteins coded by these two genes function cell-non-autonomously and that their activity depends upon conserved cysteines, making them good candidate for being involved in the transmission of a reactive oxygen species (ROS) signal generated by the PaNox1 NADPH oxidase inside the maturing fruiting body towards the PaMpk1 MAP kinase, which is located inside the underlying mycelium, in which nutrients are stored. These data provide important new insights to our understanding of how fungi build multicellular structures.

Dates and versions

hal-03153117 , version 1 (26-02-2021)

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Herve Lalucque, Fabienne Malagnac, Kimberly Green, Valérie Gautier, Pierre Grognet, et al.. IDC2 and IDC3 , two genes involved in cell non-autonomous signaling of fruiting body development in the model fungus Podospora anserina. Developmental Biology, 2017, 421 (2), pp.126-138. ⟨10.1016/j.ydbio.2016.12.016⟩. ⟨hal-03153117⟩
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