Nonlinear viscoelastic constitutive model for bovine liver tissue - Université Paris Cité Accéder directement au contenu
Article Dans Une Revue Biomechanics and Modeling in Mechanobiology Année : 2020

Nonlinear viscoelastic constitutive model for bovine liver tissue

Adela Capilnasiu
Lynne Bilston
  • Fonction : Auteur
Ralph Sinkus
David Nordsletten

Résumé

Abstract Soft tissue mechanical characterisation is important in many areas of medical research. Examples span from surgery training, device design and testing, sudden injury and disease diagnosis. The liver is of particular interest, as it is the most commonly injured organ in frontal and side motor vehicle crashes, and also assessed for inflammation and fibrosis in chronic liver diseases. Hence, an extensive rheological characterisation of liver tissue would contribute to advancements in these areas, which are dependent upon underlying biomechanical models. The aim of this paper is to define a liver constitutive equation that is able to characterise the nonlinear viscoelastic behaviour of liver tissue under a range of deformations and frequencies. The tissue response to large amplitude oscillatory shear (1–50%) under varying preloads (1–20%) and frequencies (0.5–2 Hz) is modelled using viscoelastic-adapted forms of the Mooney–Rivlin, Ogden and exponential models. These models are fit to the data using classical or modified objective norms. The results show that all three models are suitable for capturing the initial nonlinear regime, with the latter two being capable of capturing, simultaneously, the whole deformation range tested. The work presented here provides a comprehensive analysis across several material models and norms, leading to an identifiable constitutive equation that describes the nonlinear viscoelastic behaviour of the liver.

Dates et versions

hal-03406325 , version 1 (27-10-2021)

Identifiants

Citer

Sinkus Ralph, Adela Capilnasiu, Lynne Bilston, Ralph Sinkus, David Nordsletten. Nonlinear viscoelastic constitutive model for bovine liver tissue. Biomechanics and Modeling in Mechanobiology, 2020, 19 (5), pp.1641-1662. ⟨10.1007/s10237-020-01297-5⟩. ⟨hal-03406325⟩
13 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More