Cohort description: Measures of early-life behaviour and later psychopathology in the LifeCycle Project - EU Child Cohort Network - Université Paris Cité Accéder directement au contenu
Article Dans Une Revue Journal of Epidemiology Année : 2023

Cohort description: Measures of early-life behaviour and later psychopathology in the LifeCycle Project - EU Child Cohort Network

1 NIPH - Norwegian Institute of Public Health [Oslo]
2 ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona]
3 Erasmus MC - Erasmus University Medical Center [Rotterdam]
4 IISPV - Institut d'Investigació Sanitària Pere Virgili [Tarragona]
5 MRC Integrative Epidemiology Unit
6 University of Bristol [Bristol]
7 University of Oulu
8 MRC Oulu - Medical Research Center Oulu [Oulu]
9 The Generation R Study Group
10 iPLESP - Institut Pierre Louis d'Epidémiologie et de Santé Publique
11 CRESS (U1153 / UMR_A 1125) - Centre for Research in Epidemiology and Statistics | Centre de Recherche Épidémiologie et Statistiques
12 ELFE - Etude longitudinale française depuis l'enfance (UMS : Ined-Inserm-EFS)
13 BIHR - Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK
14 MUL - Medical University of Łódź
15 Telethon KIDS Institute
16 CPO Piemonte - Centro di Riferimento per l'Epidemiologia e la Prevenzione Oncologica in Piemonte = Center for Cancer Prevention-Piemonte
17 UMCG - University Medical Center Groningen [Groningen]
18 Folkhälsan Research Center
19 Helsingin yliopisto = Helsingfors universitet = University of Helsinki
20 National Institute for Health and Welfare [Helsinki]
21 HUS - Helsinki University Hospital [Finland]
22 SICS - Singapore Institute for Clinical Sciences [Singapour]
23 Yong Loo Lin School of Medicine [Singapore]
24 Southampton General Hospital
25 NIHR Biomedical Research Centre [London]
26 Department of Public Health [Copenhagen]
27 Dr von Hauner Children's Hospital [Munich, Germany]
28 UOC - University of Crete [Heraklion]
Nina Rautio
  • Fonction : Auteur
Jennie Carson
Rae-Chi Huang

Résumé

Background: The EU LifeCycle Project was launched in 2017 to combine, harmonise, and analyse data from more than 250,000 participants across Europe and Australia, involving cohorts participating in the EU-funded LifeCycle Project. The purpose of this cohort description is to provide a detailed overview over the major measures within mental health domains that are available in 17 European and Australian cohorts participating in the LifeCycle Project. Methods: Data on cognitive, behavioural and psychological development has been collected on participants from birth until adulthood through questionnaire and medical data. We developed an inventory of the available data by mapping individual instruments, domain types, and age groups, providing the basis for statistical harmonization across mental health measures. Results: The mental health data in LifeCycle contain longitudinal and cross-sectional data for ages 0-18+ years, covering domains across a wide range of behavioural and psychopathology indicators and outcomes (including executive function, depression, ADHD and cognition). These data span a unique combination of qualitative data collected through behavioural/cognitive/mental health questionnaires and examination, as well as data from biological samples and indices in the form of brain imaging (MRI, foetal ultrasound) and DNA methylation data. Harmonized variables on a subset of mental health domains have been developed, providing statistical equivalence of measures required for longitudinal meta-analyses across instruments and cohorts. Conclusion: Mental health data harmonized through the LifeCycle project can be used to study life course trajectories and exposure-outcome models that examine early life risk factors for mental illness and develop predictive markers for later-life disease.
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Origine : Publication financée par une institution

Dates et versions

hal-03522806 , version 1 (12-01-2022)

Identifiants

Citer

Johanna L. Nader, Mònica López-Vicente, Jordi Julvez, Monica Guxens, Tim Cadman, et al.. Cohort description: Measures of early-life behaviour and later psychopathology in the LifeCycle Project - EU Child Cohort Network. Journal of Epidemiology, In press, 33 (6), pp.321-331. ⟨10.2188/jea.JE20210241⟩. ⟨hal-03522806⟩
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