Metabolic Oxidative Cleavage of Thioesters: Evidence for the Formation of Sulfenic Acid Intermediates in the Bioactivation of the Antithrombotic Prodrugs Ticlopidine and Clopidogrel - Université Paris Cité Accéder directement au contenu
Article Dans Une Revue Chemical Research in Toxicology Année : 2009

Metabolic Oxidative Cleavage of Thioesters: Evidence for the Formation of Sulfenic Acid Intermediates in the Bioactivation of the Antithrombotic Prodrugs Ticlopidine and Clopidogrel

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hal-03684993 , version 1 (01-06-2022)

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Patrick Dansette, Julie Libraire, Gildas Bertho, Daniel Mansuy. Metabolic Oxidative Cleavage of Thioesters: Evidence for the Formation of Sulfenic Acid Intermediates in the Bioactivation of the Antithrombotic Prodrugs Ticlopidine and Clopidogrel. Chemical Research in Toxicology, 2009, 22 (2), pp.369-373. ⟨10.1021/tx8004828⟩. ⟨hal-03684993⟩

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