Dynamic contrast enhanced magnetic resonance imaging: A review of its application in the assessment of placental function - Université Paris Cité Accéder directement au contenu
Article Dans Une Revue (Article De Synthèse) Placenta Année : 2021

Dynamic contrast enhanced magnetic resonance imaging: A review of its application in the assessment of placental function

Résumé

It is important to develop a better understanding of placental insufficiency given its role in common maternofetal complications such as preeclampsia and fetal growth restriction. Functional magnetic resonance imaging offers unprecedented techniques for exploring the placenta under both normal and pathological physiological conditions. Dynamic contrast-enhanced magnetic resonance imaging (DCE MRI) is an established and very robust method to investigate the microcirculatory parameters of an organ and more specifically its perfusion. It is currently a gold standard in the physiological and circulatory evaluation of an organ. Its application to the human placenta could enable to access many microcirculatory parameters relevant to the placental function such as organ blood flow, fractional blood volume, and permeability surface area, by the acquisition of serial images, before, during, and after administration of an intravenous contrast agent. Widely used in animal models with gadolinium-based contrast agents, its application to the human placenta could be possible if the safety of contrast agents in pregnancy is established or they are confirmed to not cross the placenta.
Fichier principal
Vignette du fichier
S0143400421005634.pdf (832.44 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03790050 , version 1 (16-10-2023)

Licence

Paternité - Pas d'utilisation commerciale

Identifiants

Citer

Mathilde Jacquier, Chloé Arthuis, David Grévent, Laurence Bussières, Charline Henry, et al.. Dynamic contrast enhanced magnetic resonance imaging: A review of its application in the assessment of placental function. Placenta, 2021, 114, pp.90-99. ⟨10.1016/j.placenta.2021.08.055⟩. ⟨hal-03790050⟩
8 Consultations
12 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More