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Article Dans Une Revue Journal of Psychiatric Research Année : 2021

Prevalence and incidence of postpartum depression and environmental factors: the IGEDEPP cohort

Emmanuelle Bertin
  • Fonction : Auteur
Cecile Bourneuf
  • Fonction : Auteur
Jeanne Colombe
  • Fonction : Auteur
Laura Couppa
  • Fonction : Auteur
Marc Dommergue
  • Fonction : Auteur
Celine Hebbache
  • Fonction : Auteur
Marie Le Bars
  • Fonction : Auteur
Julie Guiot Madhavi
  • Fonction : Auteur
Cindy Parent
  • Fonction : Auteur

Résumé

Background: IGEDEPP (Interaction of Gene and Environment of Depression during PostPartum) is a prospective multicenter cohort study of 3,310 Caucasian women who gave birth between 2011 and 2016, with follow-up until one year postpartum. The aim of the current study is to describe the cohort and estimate the prevalence and cumulative incidence of early and late-onset postpartum depression (PPD). Methods: Socio-demographic data, personal and family psychiatric history, as well as stressful life events during childhood and pregnancy were evaluated at baseline. Early and late-onset PPD were assessed at 8 weeks and 1 year postpartum respectively, using DSM-5 criteria. Results: The prevalence of early-onset PPD was 8.3% (95%CI 7.3-9.3), and late PPD 12.9% (95%CI 11.5- 14.2), resulting in an 8-week cumulative incidence of 8.5% (95%CI 7.4-9.6) and a one-year cumulative incidence of PPD of 18.1% (95%CI: 17.1-19.2). Nearly half of the cohort (N=1571, 47.5%) had a history of at least one psychiatric or addictive disorder, primarily depressive disorder (35%). Almost 300 women in the cohort (9.0%) reported childhood trauma. During pregnancy, 47.7% women experienced a stressful event, 30.2% in the first 8 weeks and 43.9% between 8 weeks and one year postpartum. Nearly one in five women reported at least one stressful postpartum event at 8 weeks. Conclusion: Incident depressive episodes affected nearly one in five women during the first year postpartum. Most women had stressful perinatal events. Further IGEDEPP studies will aim to disentangle the impact of childhood and pregnancy-related stressful events on postpartum mental disorders.
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hal-03854480 , version 1 (15-11-2022)

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Sarah Tebeka, Yann Le Strat, Alix De Premorel Higgons, Alexandra Benachi, Marc Dommergues, et al.. Prevalence and incidence of postpartum depression and environmental factors: the IGEDEPP cohort. Journal of Psychiatric Research, 2021, 138, pp.366-374. ⟨10.1016/j.jpsychires.2021.04.004⟩. ⟨hal-03854480⟩
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