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authFullName_s : Ivan Bieche
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Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers

Rana Hatem , Rania El Botty , Sophie Chateau-Joubert , Jean Luc Servely , Dalila Labiod et al.
Oncotarget, 2016, 7 (30), pp.48206-48219. ⟨10.18632/oncotarget.10195⟩
Journal articles hal-01604166v1

Intratumoral microbiome is driven by metastatic site and associated with immune histopathological parameters: An ancillary study of the SHIVA clinical trial

Marc Hilmi , Maud Kamal , Sophie Vacher , Célia Dupain , Sabrina Ibadioune et al.
European Journal of Cancer, 2023, 183, pp.152-161. ⟨10.1016/j.ejca.2023.01.024⟩
Journal articles hal-04094778v1

Cytidine Deaminase Deficiency Reveals New Therapeutic Opportunities against Cancer

Hamza Mameri , Ivan Bieche , Didier Meseure , Elisabetta Marangoni , Géraldine Buhagiar-Labarchède et al.
Clinical Cancer Research, 2017, 23 (8), pp.2116-2126. ⟨10.1158/1078-0432.CCR-16-0626⟩
Journal articles hal-02345988v1

CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer’s disease

Sophie Ayciriex , Fathia Djelti , Jérome Braudeau , Eloise Hudry , Marc Dhenain et al.
Brain - A Journal of Neurology , 2015, 138 (8), pp.2383 - 2398. ⟨10.1093/brain/awv166⟩
Journal articles hal-01779044v1

Microsatellite instability detection in breast cancer using drop-off droplet digital PCR

Khadidja Zeyneb Klouch , Marc Henri Stern , Olfa Trabelsi-Grati , Nicolas Kiavue , Luc Cabel et al.
Oncogene, 2022, 41 (49), pp.5289-5297. ⟨10.1038/s41388-022-02504-6⟩
Journal articles hal-03949622v1
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Identification of the first intragenic deletion of the PITX2 gene causing an Axenfeld-Rieger Syndrome: case report.

Guillaume de La Houssaye , Ivan Bieche , Olivier Roche , Véronique Vieira , Ingrid Laurendeau et al.
BMC Medical Genetics, 2006, 7 (2), pp.82. ⟨10.1186/1471-2350-7-82⟩
Journal articles inserm-00121215v1

Involvement of the FOXO6 transcriptional factor in breast carcinogenesis

François Lallemand , Ambre Petitalot , Sophie Vacher , Leanne De Koning , Karim Taouis et al.
Oncotarget, 2018, 9 (7), pp.7464--7475. ⟨10.18632/oncotarget.23779⟩
Journal articles hal-02180792v1

Molecular profiling of non-small-cell lung cancer patients with or without brain metastases included in the randomized SAFIR02-LUNG trial and association with intracranial outcome

Alice Mogenet , Fabrice Barlesi , Benjamin Besse , Stefan Michiels , Maryam Karimi et al.
Lung Cancer, 2022, 169, pp.31-39. ⟨10.1016/j.lungcan.2022.05.004⟩
Journal articles hal-03925563v1

Prognostic value of a newly identified MALAT1 alternatively spliced transcript in breast cancer

Didier Meseure , Sophie Vacher , François Lallemand , Kinan Drak Alsibai , Rana Hatem et al.
British Journal of Cancer, 2016, 114 (12), pp.1395-1404. ⟨10.1038/bjc.2016.123⟩
Journal articles hal-02349825v1
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Vasculature analysis of patient derived tumor xenografts using species-specific PCR assays: evidence of tumor endothelial cells and atypical VEGFA-VEGFR1/2 signalings.

Ivan Bieche , Sophie Vacher , David Vallerand , Sophie Richon , Rana Hatem et al.
BMC Cancer, 2014, 14 (1), pp.178. ⟨10.1186/1471-2407-14-178⟩
Journal articles inserm-00980902v1
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NF1 microdeletions in neurofibromatosis type 1: from genotype to phenotype

Eric Pasmant , Audrey Sabbagh , Gill Spurlock , Ingrid Laurendeau , Elisa Grillo et al.
Human Mutation, 2010, 31 (6), pp.E1506-E1518. ⟨10.1002/humu.21271⟩
Journal articles istex hal-00552390v1
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The high protein expression of FOXO3, but not that of FOXO1, is associated with markers of good prognosis

François Lallemand , Sophie Vacher , Leanne de Koning , Ambre Petitalot , Adrien Briaux et al.
Scientific Reports, 2020, 10, ⟨10.1038/s41598-020-63895-8⟩
Journal articles hal-03064332v1

Real-Time Detection of ESR1 Mutation in Blood by Droplet Digital PCR in the PADA-1 Trial: Feasibility and Cross-Validation with NGS

Celine Callens , François Clément Bidard , Anaïs Curto-Taribo , Olfa Trabelsi-Grati , Samia Melaabi et al.
Analytical Chemistry, 2022, 94 (16), pp.6297-6303. ⟨10.1021/acs.analchem.2c00446⟩
Journal articles hal-03673620v1
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Genomic Instability Signature of Palindromic Non-Coding Somatic Mutations in Bladder Cancer

Sophie Vacher , Voreak Suybeng , Élodie Girard , Julien Masliah Planchon , Grégory Thomson et al.
Cancers, 2020, 12 (10), pp.2882. ⟨10.3390/cancers12102882⟩
Journal articles hal-03011747v1

Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology

Sophie Ayciriex , Marie-Anne Burlot , Jérome Braudeau , Kristin Michaelsen-Preusse , Brigitte Potier et al.
Human Molecular Genetics, 2015, 24 (21), pp.5965 - 5976. ⟨10.1093/hmg/ddv268⟩
Journal articles hal-01779042v1

Evolution of synchronous female bilateral breast cancers and response to treatment

Anne-Sophie Hamy , Judith Abécassis , Keltouma Driouch , Lauren Darrigues , Mathias Vandenbogaert et al.
Nature Medicine, 2023, ⟨10.1038/s41591-023-02216-8⟩
Journal articles hal-04020231v1

Identification of new candidate therapeutic target genes in head and neck squamous cell carcinomas

Marie Paule Sablin , Coraline Dubot , Jerzy T. Klijanienko , Sophie Vacher , Lamia Ouafi et al.
Oncotarget, 2016, 7 (30), pp.47418-47430. ⟨10.18632/oncotarget.10163⟩
Journal articles hal-02559121v1
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Prognostic value of intratumoral Fusobacterium nucleatum and association with immune-related gene expression in oral squamous cell carcinoma patients

Cindy Neuzillet , Manon Marchais , Sophie Vacher , Marc Hilmi , Anne Schnitzler et al.
Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-86816-9⟩
Journal articles hal-03242705v1

Comprehensive Genome Profiling in Patients With Metastatic Non-Small Cell Lung Cancer: The Precision Medicine Phase II Randomized SAFIR02-Lung Trial

Sandrine Boyault , Valery Attignon , Isabelle Soubeyran , Alain Morel , Alicia Tran-Dien et al.
CLINICAL CANCER RESEARCH, 2022, 28 (18), pp.4018-4026. ⟨10.1158/1078-0432.CCR-22-0371⟩
Journal articles hal-04084975v1
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A large collection of integrated genomically characterized patient‐derived xenografts highlighting the heterogeneity of triple‐negative breast cancer

Florence Coussy , Leanne Koning , Marion Lavigne , Virginie Bernard , Berengere Ouine et al.
International Journal of Cancer, 2019, ⟨10.1002/ijc.32266⟩
Journal articles hal-02093370v1
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Assessment of prognostic implication of a panel of oncogenes in bladder cancer and identification of a 3-gene signature associated with recurrence and progression risk in non-muscle-invasive bladder cancer

Constance Le Goux , Sophie Vacher , Anne Schnitzler , Nicolas Barry Delongchamps , Marc Zerbib et al.
Scientific Reports, 2020, 10 (1), pp.16641. ⟨10.1038/s41598-020-73642-8⟩
Journal articles hal-02986867v1

Feasibility and clinical integration of molecular profiling for target identification in pediatric solid tumors

Thomas Pincez , Nathalie Clément , Eve Lapouble , Gäelle L. Pierron , Maud Kamal et al.
Pediatric Blood and Cancer, 2017, 64 (6), ⟨10.1002/pbc.26365⟩
Journal articles hal-02558637v1
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Immune gene expression in head and neck squamous cell carcinoma patients

Charlotte Lecerf , Maud Kamal , Sophie Vacher , Walid Chemlali , Anne Schnitzler et al.
European Journal of Cancer, 2019, 121, pp.210 - 223. ⟨10.1016/j.ejca.2019.08.028⟩
Journal articles hal-03488906v1
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Pharmacologic Normalization of Pancreatic Cancer-Associated Fibroblast Secretome Impairs Prometastatic Cross-Talk With Macrophages

Rémi Samain , Alexia Brunel , Thibaut Douché , Marjorie Fanjul , Stéphanie Cassant-Sourdy et al.
Cellular and Molecular Gastroenterology and Hepatology, 2021, 11 (5), pp.1405-1436. ⟨10.1016/j.jcmgh.2021.01.008⟩
Journal articles pasteur-03252986v1
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Biopathological Significance of PIWI–piRNA Pathway Deregulation in Invasive Breast Carcinomas

Didier Meseure , Sophie Vacher , Sabah Boudjemaa , Marick Laé , André Nicolas et al.
Cancers, 2020, 12 (10), pp.2833. ⟨10.3390/cancers12102833⟩
Journal articles hal-03011561v1
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IFI35, mir-99a and HCV Genotype to Predict Sustained Virological Response to Pegylated-Interferon Plus Ribavirin in Chronic Hepatitis C

Emilie Estrabaud , Kevin Appourchaux , Ivan Bieche , Fabrice Carrat , Martine Lapalus et al.
PLoS ONE, 2015, 10 (4), pp.e0121395. ⟨10.1371/journal.pone.0121395⟩
Journal articles hal-01233435v1