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authFullName_s : Patrice Rat

Comparative study of topical anti-allergic eye drops on human conjunctiva-derived cells: responses to histamine and IFNγ and toxicological profiles

Aude Pauly , Françoise Brignole-Baudouin , Jean-Marc Guenoun , Luisa Riancho , Patrice Rat et al.
Graefe's Archive for Clinical and Experimental Ophthalmology, 2007, 245 (4), pp.534-546. ⟨10.1007/s00417-006-0353-z⟩
Journal articles istex hal-02538568v1

Forskolin Induces Endocrine Disturbance in Human JEG-3 Placental Cells

Patrice Rat , Pascale Leproux , Sophie Fouyet , Elodie Olivier
Toxics, 2022, 10 (7), pp.355. ⟨10.3390/toxics10070355⟩
Journal articles hal-03837745v1

Cell cooperation and role of the P2X7 receptor in pulmonary inflammation induced by nanoparticles

Samir Dekali , Ariane Divetain , Thierry Kortulewski , Justine Vanbaelinghem , Christelle Gamez et al.
Nanotoxicology, 2013, 7 (8), pp.1302-1314. ⟨10.3109/17435390.2012.735269⟩
Journal articles ineris-00963497v1

Poloxamer bioadhesive hydrogel for buccal drug delivery: Cytotoxicity and trans-epithelial permeability evaluations using TR146 human buccal epithelial cell line

Ni Zeng , Nathalie Mignet , Gilles Dumortier , Elodie Olivier , Johanne Seguin et al.
International Journal of Pharmaceutics, 2015, 495 (2), pp.1028-1037. ⟨10.1016/j.ijpharm.2015.09.045⟩
Journal articles hal-03290547v1
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Formulation and cytotoxicity evaluation of new self-emulsifying multiple W/O/W nanoemulsions

Estelle Sigward , Nathalie Mignet , Patrice Rat , Melody Dutot , Saleh Muhamed et al.
International Journal of Nanomedicine, 2013, 8, pp.611 - 625. ⟨10.2147/IJN.S35661⟩
Journal articles hal-01583935v1

Perception of pharmacy students toward opioid-related disorders and roles of community pharmacists: A French nationwide cross-sectional study

David Balayssac , Bruno Pereira , Pierre Cuq , Juliette Douris , Luc Ferrari et al.
Substance Abuse, 2021, 42 (4), pp.706-715. ⟨10.1080/08897077.2020.1850607⟩
Journal articles hal-03077594v1
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Assessment of an in vitro model of pulmonary barrier to study the translocation of nanoparticles

Samir Dekali , Christelle Gamez , Thierry Kortulewski , Kelly Blazy , Patrice Rat et al.
Toxicology Reports, 2014, 1, pp.157-171. ⟨10.1016/j.toxrep.2014.03.003⟩
Journal articles ineris-01855550v1

The Role of the P2X7 Receptor in Ocular Stresses: A Potential Therapeutic Target

Mélody Dutot , Elodie Olivier , Anaïs Wakx , Patrice Rat
Vision, 2017, 1 (2), pp.14. ⟨10.3390/vision1020014⟩
Journal articles hal-03837739v1
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The Wound Healing and Antibacterial Activity of Five Ethnomedical Calophyllum inophyllum Oils

Teddy Léguillier , Marylin Lecsö-Bornet , Christelle Lémus , Delphine Rousseau-Ralliard , Nicolas Lebouvier et al.
PLoS ONE, 2015, 10 (9), pp.1-20. ⟨10.1371/journal.pone.0138602⟩
Journal articles hal-01681946v1

In Vitro Chemopreventive Potential of Phlorotannins-Rich Extract from Brown Algae by Inhibition of Benzo[a]pyrene-Induced P2X7 Activation and Toxic Effects

Mélody Dutot , Elodie Olivier , Sophie Fouyet , Romain Magny , Karim Hammad et al.
Marine drugs, 2021, 19 (1), pp.34. ⟨10.3390/md19010034⟩
Journal articles hal-03367638v1

P2X7-pannexin-1 and amyloid β-induced oxysterol input in human retinal cell: Role in age-related macular degeneration?

Elodie Olivier , Mélody Dutot , Anne Regazzetti , Teddy Leguillier , Delphine Dargère et al.
Biochimie, 2016, 127, pp.70-78. ⟨10.1016/j.biochi.2016.04.014⟩
Journal articles hal-03837753v1

Effet de la fonctionnalisation de surface des nanoparticules sur leur internalisation et sur les dommages causés à l'ADN

Samir Dekali , Vincent Paget , Thierry Kortulewski , Romain Grall , Sylvie Chevillard et al.
Congrès annuel de la Société Française de Toxicologie "Relations entre Recherche, Evaluation du Risque et Règlementation", Nov 2012, Toulouse, France
Conference papers ineris-00971078v1
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Per os administered refined olive oil and marine PUFA-rich oils reach the cornea: possible role on oxidative stress through caveolin-1 modulation

Melody Dutot , Hong Liang , Chantal Martin , Delphine Rousseau , Alain Grynberg et al.
Nutrition and Metabolism, 2009, 6, pp.1-9. ⟨10.1186/1743-7075-6-48⟩
Journal articles hal-02668144v1
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Specific uptake and genotoxicity induced by polystyrene nanobeads with distinct surface chemistry on human lung epithelial cells and macrophages

Vincent Paget , Samir Dekali , Thierry Kortulewski , Romain Grall , Christelle Gamez et al.
PLoS ONE, 2015, 10 (4), e0123297. ⟨10.1371/journal.pone.0123297⟩
Journal articles ineris-01862554v1

Characterization of a new coculture model of alveolo-capillary barrier developed to study the translocation and the toxicity of nanoparticles

Samir Dekali , Christelle Gamez , Françoise Rogerieux , Patrice Rat , Ghislaine Lacroix et al.
47. European Congress of Toxicology (EUROTOX 2011), Aug 2011, Paris, France
Conference papers ineris-00970855v1

Inflammatory response study on a new coculture model of alveolo-capillary barrier treated by TiO2 and SiO2 nanoparticles

Samir Dekali , Christelle Gamez , Françoise Rogerieux , Ghislaine Lacroix , Patrice Rat et al.
10. World Congress on Inflammation "Translating basic research to patient care", Jun 2011, Paris, France
Conference papers ineris-00970839v1

Specific uptakes and damages induced by polystyrene nanobeads according to surface chemistry

Vincent Paget , Samir Dekali , Thierry Kortulewski , Romain Grall , Sylvie Chevillard et al.
3. International Conference on Safe Production and Use of Nanomaterials (Nanosafe 2012), Nov 2012, Grenoble, France
Conference papers ineris-00971087v1

AβPP-induced UPR Transcriptomic Signature of Glial Cells to Oxidative Stress as an Adaptive Mechanism to Preserve Cell Function and Survival

Naima Chalour , Agathe Maoui , Patrice Rat , France Massicot , Melody Dutot et al.
Current Alzheimer Research, 2018, 15 (7), pp.643-654. ⟨10.2174/1567205015666180119101832⟩
Journal articles hal-02461733v1

25-Hydroxycholesterol induces both P2X7-dependent pyroptosis and caspase-dependent apoptosis in human skin model: New insights into degenerative pathways

Elodie Olivier , Mélody Dutot , Anne Regazzetti , Olivier Laprévote , Patrice Rat et al.
Chemistry and Physics of Lipids, 2017, 207, pp.171-178. ⟨10.1016/j.chemphyslip.2017.06.001⟩
Journal articles hal-03837758v1

A fast and reproducible cell- and 96-well plate-based method for the evaluation of P2X7 receptor activation using YO-PRO-1 fluorescent dye

Patrice Rat , Elodie OLIVIER , Caroline Tanter , Anaïs Wakx , Mélody Dutot et al.
Journal of Biological Methods, 2017, 4 (1), pp.e64. ⟨10.14440/jbm.2017.136⟩
Journal articles hal-03837761v1

3D model of air-blood barrier for the study of nanoparticles translocation

Samir Dekali , Vincent Paget , Christelle Gamez , Patrice Rat , Ghislaine Lacroix et al.
3. International Conference on Safe Production and Use of Nanomaterials (Nanosafe 2012), Nov 2012, Grenoble, France
Conference papers ineris-00971088v1
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Cytotoxic and Anti-Inflammatory Effects of Ent-Kaurane Derivatives Isolated from the Alpine Plant Sideritis hyssopifolia

Axelle Aimond , Kevin Calabro , Coralie Audoin , Elodie Olivier , Melody Dutot et al.
Molecules, 2020, 25 (3), pp.589. ⟨10.3390/molecules25030589⟩
Journal articles hal-02460210v1
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In Situ Gelling Ophthalmic Drug Delivery System for the Optimization of Diagnostic and Preoperative Mydriasis: In Vitro Drug Release, Cytotoxicity and Mydriasis Pharmacodynamics

Pierre-Louis Destruel , Ni Zeng , Françoise Brignole-Baudouin , Sophie Douat , Johanne Seguin et al.
Pharmaceutics, 2020, 12 (4), pp.360. ⟨10.3390/pharmaceutics12040360⟩
Journal articles hal-02798293v1
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Lipidomic analysis of human corneal epithelial cells exposed to ocular irritants highlights the role of phospholipid and sphingolipid metabolisms in detergent toxicity mechanisms

Romain Magny , Nicolas Auzeil , Elodie Olivier , Karima Kessal , Anne Regazzetti et al.
Biochimie, 2020, 178, pp.148-157. ⟨10.1016/j.biochi.2020.07.015⟩
Journal articles hal-03032289v1