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Article Dans Une Revue JMIR Research Protocols Année : 2019

The Adverse Drug Reactions From Patient Reports in Social Media Project: Protocol for an Evaluation Against a Gold Standard

Xiaoyi Chen
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  • PersonId : 752823
  • IdHAL : xiaoyi-chen
Myrtille Deldossi
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Rim Aboukhamis
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Carole Faviez
Sylvie Guillemin-Lanne
  • Fonction : Auteur
Nathalie Texier
  • Fonction : Auteur

Résumé

Social media is a potential source of information on postmarketing drug safety surveillance that still remains unexploited nowadays. Information technology solutions aiming at extracting adverse reactions (ADRs) from posts on health forums require a rigorous evaluation methodology if their results are to be used to make decisions. First, a gold standard, consisting of manual annotations of the ADR by human experts from the corpus extracted from social media, must be implemented and its quality must be assessed. Second, as for clinical research protocols, the sample size must rely on statistical arguments. Finally, the extraction methods must target the relation between the drug and the disease (which might be either treated or caused by the drug) rather than simple co-occurrences in the posts.
RR1-10.2196/11448.
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Dates et versions

hal-03253382 , version 1 (16-12-2023)

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Armelle Arnoux-Guenegou, Yannick Girardeau, Xiaoyi Chen, Myrtille Deldossi, Rim Aboukhamis, et al.. The Adverse Drug Reactions From Patient Reports in Social Media Project: Protocol for an Evaluation Against a Gold Standard. JMIR Research Protocols, 2019, 8 (5), pp.e11448. ⟨10.2196/11448⟩. ⟨hal-03253382⟩
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