No SARS-CoV-2 reinfection among staff health-care workers: Prospective hospital-wide screening during the first and second waves in Paris - Université Paris Cité Accéder directement au contenu
Article Dans Une Revue Journal of Clinical Virology Année : 2021

No SARS-CoV-2 reinfection among staff health-care workers: Prospective hospital-wide screening during the first and second waves in Paris

Résumé

Objectives Risk of reinfection with SARS-CoV-2 among health-care workers (HCWs) is unknown. We assessed the incidence rate of SARS-CoV-2 reinfection in the real-life setting of a longitudinal observational cohort of HCWs from the Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris, France, during the first and second waves of COVID-19 epidemic. Methods From March to December 2020, HCWs were subjected to molecular and serology testing of SARS-CoV-2. Reinfection was defined as a positive test result during the first wave, either by serology or PCR, followed by a positive PCR during the second wave. Evolution of COVID-19 status of HWCs was assessed by a Sankey diagram. Results A total of 7765 tests (4579 PCR and 3186 serology) were carried out and 4168 HCWs had at least one test result during the follow-up period with a positivity rate of 15.9%. No case of reinfection during the second wave could be observed among 102 positive HCWs of the first wave, nor among 175 HCWs found positive by PCR during the second wave who were negative during the first wave. Conclusions SARS-CoV-2 reinfection was not observed among HCWs, suggesting a protective immunity against reinfection that lasts at least 8 months post infection.
Fichier principal
Vignette du fichier
Wack et al. - 2021 - No SARS-CoV-2 reinfection among staff health-care .pdf (880.23 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03405624 , version 1 (27-10-2021)

Identifiants

Citer

Maxime Wack, Hélène Péré, Nathalie Demory-Guinet, Najiby Kassis-Chikhani, Laurence Janot, et al.. No SARS-CoV-2 reinfection among staff health-care workers: Prospective hospital-wide screening during the first and second waves in Paris. Journal of Clinical Virology, 2021, 145, pp.104999. ⟨10.1016/j.jcv.2021.104999⟩. ⟨hal-03405624⟩
42 Consultations
34 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More