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Article Dans Une Revue World Journal of Biological Psychiatry Année : 2022

Telomere length and mitochondrial DNA copy number in bipolar disorder: a sibling study.

Telomere length and mitochondrial DNA copy number in bipolar disorder: a sibling study.

L. Spano
  • Fonction : Auteur
B. Etain
J-L Laplanche
  • Fonction : Auteur
M. Leboyer
S. Gard
  • Fonction : Auteur
F. Bellivier
J-L. Laplanche
  • Fonction : Auteur

Résumé

An accelerated cellular aging has been observed in bipolar disorder (BD) using biomarkers such as telomere length (TL) and mitochondrial DNA copy number (mtDNAcn). Several risk factors might drive premature aging in individuals with BD, including a familial predisposition. This study compared TL and mtDNAcn between individuals with BD and their (un)-affected siblings, and explored factors that may explain proband-sibling differences.
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Dates et versions

hal-03798566 , version 1 (05-10-2022)

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Citer

L. Spano, B. Etain, J-L Laplanche, M. Leboyer, S. Gard, et al.. Telomere length and mitochondrial DNA copy number in bipolar disorder: a sibling study.. World Journal of Biological Psychiatry, 2022, pp.1-25. ⟨10.1080/15622975.2022.2131907⟩. ⟨hal-03798566⟩

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